Myeloid cell surface antigen CD33 (CD33). Sialic-acid-binding immunoglobulin-like lectin (Siglec) that plays a role in mediating cell-cell interactions and in maintaining immune cells in a resting state.
NCT03638206 - Esophagus Cancer, Renal Carcinoma, Hepatoma, Lung Cancer, Mesothelioma, Ovarian Cancer, Pancreatic Cancer, Melanoma
The following plot describes the target topology, highlighting the position of the endo-, ecto- and transmembrane domains, as well as the position of a signal peptide, when present. The last three rows describe the position of potential epitopes, as well as phosphorylation and glycosylation sites.